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Expert Process Architecture in Biomanufacturing Facility Design

Design biomanufacturing facilities where process flow, cleanroom zoning, utilities, automation, and compliance work together from day one. Hixson brings 75+ years of integrated architecture and engineering experience to help pharma and biotech teams translate complex manufacturing requirements into efficient, flexible, validation-ready facilities that support speed-to-market and long-term operational performance.

Biomanufacturing facility process architecture planning

Our Process Architecture Services

Integrated planning and engineering services for compliant, flexible, and efficient biomanufacturing environments.

Pharma Design

Hixson develops cGMP spaces for oral solid dose, sterile processing, biologics, controlled environments, clean utilities, HVAC pressurization, and documentation supporting IQ/OQ/PQ validation activities.

Biologics Facilities

Facility design for mAbs, vaccines, recombinant proteins, blood products, and biosimilars, including upstream suites, downstream purification, fill/finish, lyophilization, cleanroom HVAC, containment, and compliant documentation.

Cell Therapy

cGMP design for viral vector, plasmid DNA, CRISPR, CAR-T, autologous, and allogeneic manufacturing with ISO cleanrooms, single-use equipment integration, clean utilities, and BSL-2 containment.

Aseptic Processing

Process architecture for sterile fill/finish, prefilled syringes, ophthalmics, and aseptic biologics, integrating ISO Class 5 zones, RABS, isolators, unidirectional airflow, and Annex 1 alignment.

Modular cGMP

Design and engineering for modular cleanrooms, skid-mounted process units, and tenant cGMP fit-outs that improve speed-to-market, regulatory predictability, and future capacity flexibility.

Master Planning

Strategic master planning for cGMP zones, cleanroom expansion, clean utility infrastructure, warehouse flows, QA/QC labs, and phased capital deployment aligned with pipeline milestones.

Engineers coordinating biomanufacturing process design

Our Integrated Design Process

Define User Requirements and Process Basis

We begin by translating product, batch, throughput, segregation, containment, and regulatory needs into a clear process basis. This establishes the foundation for layouts, utilities, equipment, cleanroom classifications, and validation-supporting design deliverables.

Map Flows, Adjacencies, and cGMP Zones

Coordinate Equipment, Utilities, and Automation

Develop Documentation for Construction and Validation

Support Startup, Commissioning, and Future Expansion

Trusted By Leaders

Proven Project Experience

Hixson supports respected pharma, biotech, laboratory, food, beverage, and workplace clients across North America.

"Very cool place with nice employees."

RaiderGreg
RaiderGreg

"Love it."

Zachary Waas
Zachary Waas

"Great Group of people. Thank You for supporting Special Olympics!"

Rebekah Travis
Rebekah Travis

"Very cool place with nice employees."

RaiderGreg
RaiderGreg

"Love it."

Zachary Waas
Zachary Waas

"Great Group of people. Thank You for supporting Special Olympics!"

Rebekah Travis
Rebekah Travis

"Very cool place with nice employees."

RaiderGreg
RaiderGreg

"Love it."

Zachary Waas
Zachary Waas

"Great Group of people. Thank You for supporting Special Olympics!"

Rebekah Travis
Rebekah Travis
The Hixson Difference

Why Choose Hixson?

Hixson integrates architecture, engineering, and process knowledge to reduce risk in complex manufacturing projects.

75+ Years

Decades of architecture and engineering experience inform complex cGMP facility decisions.

Integrated Disciplines

Twenty in-house technical disciplines collaborate daily from process concept through construction administration.

Sector Expertise

Focused experience in Pharma & Biotech, Science & Technology, Food & Beverage, and Workplace.

Risk Reduction

Specialized planning, controls, utilities, and compliance expertise help improve project outcomes.

Meet The Design Leaders

Specialized leaders guide complex architecture and engineering decisions.

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John Brockmeier P.E.

Manager, Plumbing Systems & Fire Protection Engineering

John oversees the department responsible for the design and engineering of plumbing systems and fire protection engineering for a variety of project types, including new construction, building utility upgrades, utility capacity analyses, and process line additions. John and his team work with a range of systems, including domestic water, process water, hot water production, direct contact water heaters, high pressure/rinse water, compressed air, natural gas, sanitary drainage, process drainage, central sanitation systems, fire pumps, and fire sprinkler systems.

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Craig Cheevers

Manager, Controls & Automation Engineering

As the Manager of Hixson's Controls & Automation department, Craig guides the team responsible for designing, implementing, and commissioning advanced control systems and automation solutions. His responsibilities include overseeing the development of automation strategies that streamline manufacturing processes, enhance operational efficiency, and ensure seamless integration of new and existing systems.

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Warren Green, P.E.

Manager, Process Engineering

Warren leads the team providing processing design services, process optimization studies, and process commissioning and FAT, SAT, and IQ activities. He advises on waste, energy, and GHG emissions reductions, and conducts safety and dust evaluations, including PSM/HAZOP. His expertise spans all food and beverage sectors including fluid, dried and cultured dairy products, processed meat, flavors, and prepared foods. Warren is also on the IDFA Food Safety Committee and actively participates in the 3A, SSI steering committee, and work groups.

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Steve Guyer, P.E.

Manager, Civil Engineering

In his role as Manager of Civil Engineering, Steve leads the team responsible for the planning, design, and engineering of roads, stormwater hydraulics and modeling, and onsite utilities. On project work, Steve is responsible for civil site project design, specifications, technical design, and project coordination with the client, government regulatory bodies, outside consultants, and contractors. As a senior staff member with our firm, Steve also serves as a mentor to newer associates.

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Chris Jarc, P.E., PMP, LEED AP

Vice President & Director, Project Management Services

Chris, a Hixson officer and member of the Board of Directors, oversees Hixson’s Project Management, Cost Estimating, and Construction Administration departments. Chris also serves in a project management role, leading teams consisting of representatives from the client, Hixson, contractors, and vendors to effective project completion. Chris assumes overall responsibility for development of project delivery strategies, coordination of all Hixson disciplines, and facilitating effective communication and management to focus resources on delivering high-quality projects on time and within budget.

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Dave Klenk

Manager, Mechanical Engineering

Dave brings more than three decades of experience to his role as the Manager of Hixson’s Mechanical Engineering Department. His work has included the design and project management of new facilities, as well as modification of existing facilities for high technology and food processing industries. At a corporate level, Dave is a member of Hixson’s Dairy and Beverage Industry team, which works to continuously improve the value Hixson offers to the dairy industry through development of our knowledge base, services and capabilities.

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Kyle McAllister

Manager, Electrical Engineering

Kyle serves as the Manager of Hixson’s Electrical Engineering department. In this role, he oversees the team responsible for the creation and delivery of electrical designs. This includes the design of high, medium, and low voltage power distribution, lighting, telecommunications, and fire alarm systems. Kyle brings more than 15 years of experience in electrical consulting and design to his role. Areas in which Kyle specializes include electrically hazardous area classification, high- and medium-voltage power distribution, protective relaying, arc flash studies, harmonics analysis, cogeneration design, emergency systems design, and complex laboratory designs.

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Scott McGlamery, P.E.

Senior Vice President, and Director, Mechanical & Electrical Engineering

Scott, an officer of the firm, leads the teams responsible for mechanical and electrical project tasks and design, specifications, technical content, consultation during equipment selection and installation and systems start-up assistance. In addition, Scott also serves as the Quality Assurance Manager, overseeing the firm’s commitment to quality. Over Scott’s more than three decades of experience, he has worked on greenfield, brownfield, and renovation projects for food & beverage plants in all sectors, labs, pharma & biotech facilities, and workplace projects.

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Scott Wever

Manager, Manufacturing Engineering

In his role as Manager of Hixson’s Manufacturing Engineering department, Scott leads the team responsible for project consulting and coordination between client, vendor, and internal disciplines within Hixson for overall manufacturing processes, functionality, equipment, and layouts. These team members develop process flow diagrams, equipment lists, and preliminary utility requirements, as well as develop equipment layouts that range from high level master planning to detailed construction documents. In addition to this role, Scott is a member of Hixson’s Meat Industry advisory team, focusing on technologies related to the meat and plant protein industry.

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Derek Wojcikowski

Director of Architecture

Derek is the Director of Hixson’s Architecture department. In this role, Derek leads the teams who design projects for our Food & Beverage, Pharma & Biotech, Laboratory, and Workplace clients. Previously, Derek served as the Manager of Hixson’s Process Layout department, where he directed the team that plays a critical coordination role in the overall development of process models and the 3D equipment model management process. Prior to these management roles, Derek, who began his career with Hixson in 2008, served as a Project Architect.

Frequently Asked Questions

What is process architecture in biomanufacturing facility design?

Process architecture connects the manufacturing process with the physical facility. It defines how equipment, cleanrooms, personnel flows, material movement, waste routes, utilities, automation, and support spaces work together. In biomanufacturing, this planning is essential for cGMP compliance, contamination control, efficient operations, validation readiness, and future capacity flexibility.

How early should process architecture begin in a biomanufacturing project?

What biomanufacturing facility types does Hixson support?

How does process architecture support cGMP compliance?

Can Hixson help with clean utilities and process systems?

Does Hixson design modular cGMP biomanufacturing facilities?

How does Hixson reduce risk during facility design?

What information is needed to start a biomanufacturing facility design?

Need Help Defining Your Facility?

Talk with Hixson about your process, compliance, and expansion goals.

Recognized & Trusted

Awards and Recognition

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Great Place to Work

Certified organization with strong associate culture.

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Rising Giants

Ranked No. 178 by Interior Design.

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Top Sector Firm

Recognized in core specialized markets.

Plan Your Biomanufacturing Facility With Confidence

Share your process goals, project stage, and facility requirements. Hixson will help identify the right planning, architecture, engineering, and compliance path forward.

Contact Us Today

For immediate assistance, feel free to give us a direct call at +1 513-241-1230. You can also send us a quick email at info@hixson-inc.com.